Measuring Nurse Knowledge, Attitudes, and Skills in Phase 1 Clinical Trials

Nurses scored highest in knowing the goal of a phase 1 drug and lowest in knowing which phase of investigational drug they were administering. For attitudes, confidence in administering and perceived safety when administering were the lowest mean scores. More than half had administered a phase 1 drug in the past five years. More oncology nursing experience correlated with understanding the nurse's role and negatively correlated with fear. About half of the nurses identified challenges in clinical trials workflows.