Screening of Traditional Chinese Medicine Compounds Identified the Anti– <i>Helicobacter pylori</i> Effects of Alantolactone, Decursin, and Phillygenin
In vitro and in vivo experiments confirmed alantolactone, decursin, and phillygenin have significant anti-H. pylori activities and potential as new eradication drugs. However, further research is required to elucidate their specific antibacterial mechanisms.
Authors
- Chuan Xie (ORCID: https://orcid.org/0000-0001-5748-3443)
- Matthew T.V. Chan (ORCID: https://orcid.org/0000-0002-3574-7855)
- Nianshuang Li (ORCID: https://orcid.org/0000-0001-7343-9311)
- Yi Hu (ORCID: https://orcid.org/0000-0003-2708-7612)
- Biao Huang (ORCID: https://orcid.org/0000-0001-7915-5993)
- William Ka Kei Wu (ORCID: https://orcid.org/0000-0002-5662-5240)
- Cong He (ORCID: https://orcid.org/0000-0002-1185-5456)
- Xu Shu (ORCID: https://orcid.org/0000-0002-0861-5742)
- Yuanyuan Zhang (ORCID: https://orcid.org/0000-0002-3807-1248)
- Huan Wang (ORCID: https://orcid.org/0000-0003-0126-4983)
- Ling Zhang (ORCID: https://orcid.org/0000-0002-7917-7671)
- Yin Li (ORCID: https://orcid.org/0000-0002-7102-323X)
- Xiaowei Wu (ORCID: https://orcid.org/0000-0003-4176-7198)
- Nonghua Lü (ORCID: https://orcid.org/0000-0003-4373-551X)
- Yin Zhu (ORCID: https://orcid.org/0000-0002-7561-2306)
Institutions
- Jiangxi University of Traditional Chinese Medicine (CN)
- Nanchang University (CN)
- Chinese University of Hong Kong (HK)
- First Affiliated Hospital of Jiangxi Medical College (CN)
- City University of Hong Kong, Shenzhen Research Institute (CN)
- Jiang Xi Institute for Drug Control (CN)
- China Association of Acupuncture-Moxibustion (CN)
- First Affiliated Hospital of Nanchang University (CN)
- University of Hong Kong (HK)
Publication Details
- Journal
- The Journal of Infectious Diseases
- Published
- 2025-08-09
- DOI
- https://doi.org/10.1093/infdis/jiaf426
- Citations
- 1
- Primary Topic
- Helicobacter pylori-related gastroenterology studies
- Type
- article
- Field-Weighted Citation Impact
- 2.01