Recognition of Diffuse Pustules and Hemorrhagic Crusts as Early Warning Signs of Invasive Candidiasis in a Patient With Toxic Epidermal Necrolysis
Toxic Epidermal Necrolysis (TEN) is an acute, uncommon, extensive, and life-threatening dermatological condition, which is caused by a delayed adverse response of the skin to a particular type of drug. Herein, we report a 41-year-old female known case of IgA nephropathy admitted for having TEN after a recent intake of Deflazacort, developed systemic candidiasis during admission, and was successfully treated with oral fluconazole. Early detection of diffuse pustular and hemorrhagic crusted lesions with immediate antifungal treatment in TEN is crucial to prevent systemic complications and enhance patient outcomes.
Authors
- Fatemeh Saberi
- Tahereh Soori (ORCID: https://orcid.org/0000-0002-6287-4702)
- Kamran Balighi (ORCID: https://orcid.org/0000-0002-8059-670X)
- Saman Al‐Zahawi (ORCID: https://orcid.org/0009-0003-7324-0347)
- Elham Yousefi (ORCID: https://orcid.org/0000-0002-3990-7561)
Institutions
- Razi Hospital (IR)
- Tehran University of Medical Sciences (IR)
Publication Details
- Journal
- Clinical Case Reports
- Published
- 2025-11-01
- DOI
- https://doi.org/10.1002/ccr3.71451
- Citations
- 1
- Primary Topic
- Drug-Induced Adverse Reactions
- Type
- article
- Field-Weighted Citation Impact
- 1.39
Funders
- Tehran University of Medical Sciences and Health Services