Recognition of Diffuse Pustules and Hemorrhagic Crusts as Early Warning Signs of Invasive Candidiasis in a Patient With Toxic Epidermal Necrolysis

Toxic Epidermal Necrolysis (TEN) is an acute, uncommon, extensive, and life-threatening dermatological condition, which is caused by a delayed adverse response of the skin to a particular type of drug. Herein, we report a 41-year-old female known case of IgA nephropathy admitted for having TEN after a recent intake of Deflazacort, developed systemic candidiasis during admission, and was successfully treated with oral fluconazole. Early detection of diffuse pustular and hemorrhagic crusted lesions with immediate antifungal treatment in TEN is crucial to prevent systemic complications and enhance patient outcomes.

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Publication Details

Journal
Clinical Case Reports
Published
2025-11-01
DOI
https://doi.org/10.1002/ccr3.71451
Citations
1
Primary Topic
Drug-Induced Adverse Reactions
Type
article
Field-Weighted Citation Impact
1.39

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article

Recognition of Diffuse Pustules and Hemorrhagic Crusts as Early Warning Signs of Invasive Candidiasis in a Patient With Toxic Epidermal Necrolysis

Fatemeh Saberi, Tahereh Soori, Kamran Balighi, Saman Al‐Zahawi et al.
1 citations
Clinical Case Reports
Drug-Induced Adverse Reactions
1.39
article

Recognition of Diffuse Pustules and Hemorrhagic Crusts as Early Warning Signs of Invasive Candidiasis in a Patient With Toxic Epidermal Necrolysis

Fatemeh Saberi, Tahereh Soori, Kamran Balighi, Saman Al‐Zahawi, Elham Yousefi
article en
1 citations

Abstract

Toxic Epidermal Necrolysis (TEN) is an acute, uncommon, extensive, and life-threatening dermatological condition, which is caused by a delayed adverse response of the skin to a particular type of drug. Herein, we report a 41-year-old female known case of IgA nephropathy admitted for having TEN after a recent intake of Deflazacort, developed systemic candidiasis during admission, and was successfully treated with oral fluconazole. Early detection of diffuse pustular and hemorrhagic crusted lesions with immediate antifungal treatment in TEN is crucial to prevent systemic complications and enhance patient outcomes.

Clinical Case ReportsVol. 13(11)
Razi Hospital (IR), Tehran University of Medical Sciences (IR)
Tehran University of Medical Sciences and Health Services
Openalex Percentile: Top 14%
Drug-Induced Adverse Reactions
1.39
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Recognition of Diffuse Pustules and Hemorrhagic Crusts as Early Warning Signs of Invasive Candidiasis in a Patient With Toxic Epidermal Necrolysis — Fatemeh Saberi, Tahereh Soori, et al. · Clinical Case Reports (2025) | TGRS Research Map | TGRS