Modelling the impact of different intervention packages for malaria control under varying intensities of pyrethroid resistance
Compared to ITNs alone, combining ITNs with IRS and/or biolarvicides greatly improves malaria control at low to moderate intensities of pyrethroid resistance but yields no additional benefits at high resistance intensities. However, integrating these vector control strategies with immunization and effective case management using artemisinin-based combination therapy (ACT) further enhances impact by reducing both parasite transmission and the infectious reservoir.
Authors
- Maranya Mayengo (ORCID: https://orcid.org/0000-0002-1745-5509)
- Halfan S. Ngowo (ORCID: https://orcid.org/0000-0003-2789-0261)
- Fredros O. Okumu (ORCID: https://orcid.org/0000-0003-2731-5654)
- Prashanth Selvaraj (ORCID: https://orcid.org/0000-0001-7565-2300)
- Yeromin P. Mlacha (ORCID: https://orcid.org/0000-0001-8879-7066)
- Hamenyimana E Gervas
Institutions
- Ifakara Health Institute (TZ)
- Gates Foundation (US)
- The University of Dodoma (TZ)
- Institute for Disease Modeling (US)
- University of Glasgow (GB)
- Nelson Mandela African Institution of Science and Technology (TZ)
Publication Details
- Journal
- Malaria Journal
- Published
- 2025-11-19
- DOI
- https://doi.org/10.1186/s12936-025-05633-x
- Citations
- 2
- Primary Topic
- Malaria Research and Control
- Type
- article
- Field-Weighted Citation Impact
- 3.76
Funders
- Bill and Melinda Gates Foundation
- National Institute of Advanced Industrial Science and Technology
- Nelson Mandela African Institution of Science and Technology