Why Radical vs Partial Nephrectomy Matters in Patients With Preexisting Renal Dysfunction: Exploring Chronic Kidney Disease Progression by Stage
RN confers greater risk of CKD progression vs PN across preoperative CKD stages except CKD4, independent of estimated glomerular filtration rate equation. CKD2 patients demonstrated the highest relative deterioration risk. These findings suggest nephrectomy type may disproportionately affect patients with greater renal reserve, supporting broader use of PN above current guideline thresholds.
Authors
- Viraj A. Master (ORCID: https://orcid.org/0000-0002-7251-142X)
- Valentina Grajales (ORCID: https://orcid.org/0000-0002-1866-6148)
- Shreyas Joshi (ORCID: https://orcid.org/0000-0002-0020-5298)
- Jonathan Nguyen (ORCID: https://orcid.org/0000-0002-4880-8418)
- Ernest Morton (ORCID: https://orcid.org/0009-0001-9123-507X)
- Kenneth Ogan
- Mohammad Hajiha (ORCID: https://orcid.org/0000-0001-9991-7166)
- Behnam Nabavizadeh (ORCID: https://orcid.org/0000-0003-4378-9243)
- Dattatraya Patil (ORCID: https://orcid.org/0000-0002-8242-9825)
- Vikram M. Narayan (ORCID: https://orcid.org/0000-0003-3731-4209)
- Lorenzo Storino Ramacciotti (ORCID: https://orcid.org/0000-0002-0615-9720)
- Reza Nabavizadeh (ORCID: https://orcid.org/0000-0003-2230-821X)
- Sunni L. Mumford (ORCID: https://orcid.org/0000-0003-0133-3176)
- Nahar Imtiaz
- Reza Lahiji (ORCID: https://orcid.org/0009-0009-3205-3944)
- William Luke (ORCID: https://orcid.org/0009-0005-7258-5022)
- Adam Braunschweig (ORCID: https://orcid.org/0009-0001-6454-3843)
- Pooja Hemige
- Sejla Zahirovic
Institutions
- Emory University (US)
- Duke University (US)
- Cornell University (US)
- Duke Medical Center (US)
- Weill Cornell Medicine (US)
Publication Details
- Journal
- Urology Practice
- Published
- 2025-11-21
- DOI
- https://doi.org/10.1097/upj.0000000000000922
- Primary Topic
- Acute Kidney Injury Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00