Genetic plasticity of Escherichia coli causing bloodstream infections in India: A focus on phylogroups A to F
This study highlights the emerging role of phylogroup A E. coli, traditionally commensal and AMR-rich as a leading cause of BSIs in India following the acquisition of virulence factors. In parallel, B2 clones like ST131 continue to drive infections through their established virulence and resistance repertoire. Such multi-replicon IncF plasmids driving AMR-VF co-selection, calls for focused surveillance and intervention in E. coli BSIs.
Authors
- Kamini Walia (ORCID: https://orcid.org/0000-0002-1494-6919)
- G Thomas
- Irulappan Madhumathi
- Binesh Lal
- Santhosh Raj
- Ayyanraj Neeravi (ORCID: https://orcid.org/0009-0007-5891-8542)
- Karthik Gunasekaran (ORCID: https://orcid.org/0000-0002-8615-5753)
- Subbulakshmi Rajendran
- Vishnukumar Ramesh (ORCID: https://orcid.org/0009-0000-0441-1390)
- Balaji Veeraraghavan
- Venkatesh Narashiman
- Ramprakash Rayala
Institutions
- Christian Medical College, Vellore (IN)
- Indian Council of Medical Research (IN)
- Christian Medical College (IN)
Publication Details
- Journal
- Indian Journal of Medical Microbiology
- Published
- 2025-11-22
- DOI
- https://doi.org/10.1016/j.ijmmb.2025.101026
- Primary Topic
- Escherichia coli research studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00