Tripterygium wilfordii multi-glycoside alleviates ankylosing spondylitis via gut microbiota modulation and metabolite reprogramming
This study implies that GTW treatment is associated with amelioration of AS-related symptoms in mice, suggesting a potential role of the gut microbiota-metabolite axis in GTW-associated AS improvement, though causal relationships require further validation.
Authors
- Hualin Lu (ORCID: https://orcid.org/0009-0005-4838-9005)
- Xuekang Pan (ORCID: https://orcid.org/0000-0002-1936-5507)
- Chongming Wu (ORCID: https://orcid.org/0000-0003-2898-370X)
- Gang Chen (ORCID: https://orcid.org/0000-0001-5693-2702)
- Bin Chen (ORCID: https://orcid.org/0000-0002-9851-3992)
- Yanan Yang
- Mingxi Li (ORCID: https://orcid.org/0000-0003-3987-017X)
- Jiaqi Bi
Institutions
- Tianjin University of Traditional Chinese Medicine (CN)
- Jiaxing University (CN)
- First Hospital of Jiaxing (CN)
Publication Details
- Journal
- Journal of Advanced Research
- Published
- 2025-11-01
- DOI
- https://doi.org/10.1016/j.jare.2025.11.045
- Primary Topic
- Spondyloarthritis Studies and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00