Evaluating the safety and feasibility of prophylactic third-party NK cell administration in high-risk AML patients post-HSCT

Early prophylactic NK cell infusions post-HSCT are safe and feasible. Although relapse incidence remains substantial, outcomes appear improved versus historical data. Future randomized trials must confirm clinical benefits and refine timing/dosing strategies.

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Publication Details

Journal
BMC Cancer
Published
2025-11-22
DOI
https://doi.org/10.1186/s12885-025-15362-8
Primary Topic
Immune Cell Function and Interaction
Type
article
Field-Weighted Citation Impact
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article

Evaluating the safety and feasibility of prophylactic third-party NK cell administration in high-risk AML patients post-HSCT

Davoud Babakhani, Soroush Rad, Shima Tavoosi, Ghasem Janbabai et al.
BMC Cancer
Immune Cell Function and Interaction
article

Evaluating the safety and feasibility of prophylactic third-party NK cell administration in high-risk AML patients post-HSCT

Davoud Babakhani, Soroush Rad, Shima Tavoosi, Ghasem Janbabai, Shirin Tavakoli, Amir Hossein Baghsheikhi, Maryam Samareh Salavatipour, Mohammad Ahmadvand, Bahram Chahardouli, Tanaz Bahri, Maryam Barkhordar, Hossein Salehi‐Shadkami, Seied Asadollah Mousavi, Mohammad Vaezi
article en

Abstract

Early prophylactic NK cell infusions post-HSCT are safe and feasible. Although relapse incidence remains substantial, outcomes appear improved versus historical data. Future randomized trials must confirm clinical benefits and refine timing/dosing strategies.

BMC CancerVol. 25(1)
Islamic Azad University, Science and Research Branch (IR), University of Isfahan (IR), Tehran University of Medical Sciences (IR)
Openalex Percentile: Top 60%
Immune Cell Function and Interaction
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Evaluating the safety and feasibility of prophylactic third-party NK cell administration in high-risk AML patients post-HSCT — Davoud Babakhani, Soroush Rad, et al. · BMC Cancer (2025) | TGRS Research Map | TGRS