Tenecteplase for Ischemic Stroke due to Large Vessel Occlusion at 4.5 to 24 Hours: A Meta‐Analysis of Randomized Controlled Trials

This meta-analysis of randomized controlled trials manifested that tenecteplase within a 4.5- to 24-h time window of large vessel occlusion stroke was superior to control for an excellent functional outcome (mRS 0-1) without safety concerns.

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Publication Details

Journal
Brain and Behavior
Published
2025-11-01
DOI
https://doi.org/10.1002/brb3.71037
Primary Topic
Acute Ischemic Stroke Management
Type
article
Field-Weighted Citation Impact
0.00
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article

Tenecteplase for Ischemic Stroke due to Large Vessel Occlusion at 4.5 to 24 Hours: A Meta‐Analysis of Randomized Controlled Trials

Yujie Ma, Yizhe Tang, Manjun Hao, Kejia Shen et al.
Brain and Behavior
Acute Ischemic Stroke Management
article

Tenecteplase for Ischemic Stroke due to Large Vessel Occlusion at 4.5 to 24 Hours: A Meta‐Analysis of Randomized Controlled Trials

Yujie Ma, Yizhe Tang, Manjun Hao, Kejia Shen, Liyuan Wang, Shuangzhe Wu, Yige Zhang, Na Wu, Zhixin Li, Zhixin Cao, Yunyun Xiong
article en

Abstract

This meta-analysis of randomized controlled trials manifested that tenecteplase within a 4.5- to 24-h time window of large vessel occlusion stroke was superior to control for an excellent functional outcome (mRS 0-1) without safety concerns.

Brain and BehaviorVol. 15(11)
Capital Medical University (CN), Beijing Tian Tan Hospital (CN), National Clinical Research Center for Digestive Diseases (CN), Chinese Institute for Brain Research (CN)
Openalex Percentile: Top 53%
Acute Ischemic Stroke Management
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