Impact of cerebral vasospasm therapy on nimodipine exposure in subarachnoid hemorrhage: A population pharmacokinetic study
Hemodynamic augmentation therapy per se did not significantly affect [Nimodipine]<sub>plasma</sub> in contrast to patient's BSA, and, to a clinically irrelevant extent, MAP level.
Authors
- Karim Lakhal (ORCID: https://orcid.org/0000-0002-5311-3987)
- Elodie Boissier (ORCID: https://orcid.org/0000-0002-7790-6375)
- Adrien Foucher
- Matthieu Grégoire (ORCID: https://orcid.org/0000-0003-1232-5761)
- Guillaume Deslandes (ORCID: https://orcid.org/0000-0003-4587-7634)
- Jérôme E. Dauvergne (ORCID: https://orcid.org/0000-0002-9687-1059)
- Bertrand Rozec
Institutions
- Centre National de la Recherche Scientifique (FR)
- Inserm (FR)
- Centre Hospitalier Universitaire de Nantes (FR)
- Centre d'Investigation Clinique de Nantes (FR)
- Institut du Thorax (FR)
- Hôpital Laennec (FR)
- Cibles et Médicaments des Infections et de l'Immunité
- Nantes Université (FR)
Publication Details
- Journal
- Journal of the Neurological Sciences
- Published
- 2025-11-21
- DOI
- https://doi.org/10.1016/j.jns.2025.125666
- Primary Topic
- Intracranial Aneurysms: Treatment and Complications
- Type
- article
- Field-Weighted Citation Impact
- 0.00