A national cohort study examined the risk of severe infection and infection-related mortality in patients with chronic kidney disease with lupus nephritis in comparison to other chronic kidney disease etiologies
Patients with LN exhibited a higher risk of severe infection compared to patients with ANCA vasculitis, ADPKD and PGD. LN-CKD and DKD had similar infection-risks. This highlights the need for prevention and tailored immunosuppressive therapy in the LN-population with CKD.
Authors
- Anne‐Laure Faucon (ORCID: https://orcid.org/0000-0001-6716-1157)
- Mårten Segelmark (ORCID: https://orcid.org/0000-0002-1221-0772)
- Iva Gunnarsson (ORCID: https://orcid.org/0000-0002-4514-7706)
- Marie Evans (ORCID: https://orcid.org/0000-0001-8650-5795)
- Francesca Faustini (ORCID: https://orcid.org/0000-0002-6753-7107)
- Juan Jesús Carrero (ORCID: https://orcid.org/0000-0003-4763-2024)
- Peter Bárány (ORCID: https://orcid.org/0000-0001-6501-8293)
- Charikleia Chrysostomou (ORCID: https://orcid.org/0009-0009-0868-1940)
Institutions
- Karolinska University Hospital (SE)
- Inserm (FR)
- Université Paris-Saclay (FR)
- Karolinska Institutet (SE)
- Centre de recherche en Epidémiologie et Santé des Populations (FR)
- Skåne University Hospital (SE)
Publication Details
- Journal
- Kidney International
- Published
- 2025-11-21
- DOI
- https://doi.org/10.1016/j.kint.2025.10.010
- Primary Topic
- Systemic Lupus Erythematosus Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Center for Innovative Medicine