Both skeletal muscle index and muscle attenuation are associated with frailty in preoperative older patients with pancreatic cancer
Frailty and impaired functionality were associated with lower SMI and MA. Risk of delirium was independently associated with lower SMI in preoperative older patients with pancreatic cancer. These results suggests that SMI and MA should be included in standard GA screening to better identify high-risk patients and enable more targeted treatment selection.
Authors
- Nynke Michiels (ORCID: https://orcid.org/0000-0002-7518-4508)
- Shirin Feshtali
- J. Sven D. Mieog (ORCID: https://orcid.org/0000-0002-3649-8504)
- Anneke Droop
- Alexander L. Vahrmeijer (ORCID: https://orcid.org/0000-0001-9370-0011)
- Bert A. Bonsing (ORCID: https://orcid.org/0000-0003-4513-5737)
- Claudia J. Lucassen (ORCID: https://orcid.org/0000-0001-8657-1450)
- Johanneke E. A. Portielje (ORCID: https://orcid.org/0000-0002-0246-1631)
- Esteban T.D. Souwer (ORCID: https://orcid.org/0000-0003-0489-7321)
- Yaren Zügül
- Frederiek van den Bos
Institutions
- Leiden University Medical Center (NL)
- Department of Health (ZA)
Publication Details
- Journal
- Clinical Nutrition
- Published
- 2025-11-21
- DOI
- https://doi.org/10.1016/j.clnu.2025.11.004
- Primary Topic
- Nutrition and Health in Aging
- Type
- article
- Field-Weighted Citation Impact
- 0.00