Dexmedetomidine Alleviates Sleep Rhythm Abnormalities in Chronic Sleep‐Deprived Mice via Modulation of <scp>SIK3</scp> / <scp>HDAC4</scp> /5 Signalling
DEX can alleviate sleep rhythm disturbances caused by CSD in mice possibly via modulation of the SIK3/HDAC4/5 pathway, thereby improving anxiety-like behaviours and cognitive function.
Authors
- Zhouquan Wu
- Yonghong Zhou
- Yitong Ding
- Zhengye Wang
Institutions
- Changzhou No.2 People's Hospital (CN)
- Nanjing Medical University (CN)
Publication Details
- Journal
- Clinical and Experimental Pharmacology and Physiology
- Published
- 2025-11-21
- DOI
- https://doi.org/10.1111/1440-1681.70086
- Primary Topic
- Sleep and Wakefulness Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00