Does hemolysis matter after pulsed field ablation for atrial fibrillation? Insights from the Best Ablate Registry

In our study, PFA for AF was associated with an increase in hemolytic parameters, without significant short-term renal impact or occurrence of clinically significant hemolysis. Hemolysis seems to be influenced by both lesion burden and myocardial injury, highlighting the need for further investigation into the long-term clinical relevance of biomarker-defined hemolysis in PFA-treated patients.

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Publication Details

Journal
Heart Rhythm O2
Published
2025-11-22
DOI
https://doi.org/10.1016/j.hroo.2025.11.010
Primary Topic
Atrial Fibrillation Management and Outcomes
Type
article
Field-Weighted Citation Impact
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article

Does hemolysis matter after pulsed field ablation for atrial fibrillation? Insights from the Best Ablate Registry

Toshinori Chiba, Verena Tscholl, Robert Hättasch, Gerhard Hindricks et al.
Heart Rhythm O2
Atrial Fibrillation Management and Outcomes
article

Does hemolysis matter after pulsed field ablation for atrial fibrillation? Insights from the Best Ablate Registry

Toshinori Chiba, Verena Tscholl, Robert Hättasch, Gerhard Hindricks, Felix Hohendanner, C Baldauf, Nikolaos Dagres, Alireza Sepehri Shamloo, Philipp Attanasio, Philipp Formum
article en

Abstract

In our study, PFA for AF was associated with an increase in hemolytic parameters, without significant short-term renal impact or occurrence of clinically significant hemolysis. Hemolysis seems to be influenced by both lesion burden and myocardial injury, highlighting the need for further investigation into the long-term clinical relevance of biomarker-defined hemolysis in PFA-treated patients.

Heart Rhythm O2Vol. 7(2)
Deutsches Herzzentrum der Charité (DE), Charité - Universitätsmedizin Berlin (DE)
Openalex Percentile: Top 47%
Atrial Fibrillation Management and Outcomes
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Does hemolysis matter after pulsed field ablation for atrial fibrillation? Insights from the Best Ablate Registry — Toshinori Chiba, Verena Tscholl, et al. · Heart Rhythm O2 (2025) | TGRS Research Map | TGRS