Patients With Lymphedema are at Increased Risk of Complication After Total Knee Arthroplasty: A Population Level Study

Preoperative lymphedema is associated with increased 90-day rates of periprosthetic joint infection and superficial surgical site infection, wound complications, and pulmonary embolism after primary TKA. Although aseptic revision risk was not increased, the association with higher all-cause and septic revisions warrants attention. These findings emphasize the need for aggressive counseling and preoperative optimization before TKA in lymphedema patients.