Early Factors Affect the Recovery of Patients After Successful Posterior Circulation Mechanical Thrombectomy

To investigate the predictive value of clinical factors, including admission systolic blood pressure (SBP), on outcomes in patients with posterior circulation large vessel occlusion (PC-LVO) who underwent successful mechanical thrombectomy (MT), this study retrospectively enrolled patients with PC-LVO who achieved successful recanalization between January 2019 and December 2022, and assessed their 3-month survival and functional outcomes. Using univariable and multivariable logistic regression, model-fitting analyses, and receiver operating characteristic (ROC) curves, it was found that the NIH Stroke Scale score at 24 hours postprocedure (NIHSS24h) independently predicted both poor functional outcomes and mortality in recanalized PC-LVO patients. Admission SBP and age were also significantly associated with prognosis. The results indicate that early vital signs may provide important insights into the risk of poor prognosis or death after MT in PC-LVO patients. These findings offer guidance for prognostic evaluation and patient selection for mechanical thrombectomy in posterior circulation stroke.

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Publication Details

Journal
Journal of Craniofacial Surgery
Published
2025-11-21
DOI
https://doi.org/10.1097/scs.0000000000012197
Primary Topic
Acute Ischemic Stroke Management
Type
article
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article

Early Factors Affect the Recovery of Patients After Successful Posterior Circulation Mechanical Thrombectomy

Xiaochun Qin, Meng Li, Shang-biao LU, Qin Wang et al.
Journal of Craniofacial Surgery
Acute Ischemic Stroke Management
article

Early Factors Affect the Recovery of Patients After Successful Posterior Circulation Mechanical Thrombectomy

Xiaochun Qin, Meng Li, Shang-biao LU, Qin Wang, Bao He, Xiaojie Lu, Wenxuan Zhao
article en

Abstract

To investigate the predictive value of clinical factors, including admission systolic blood pressure (SBP), on outcomes in patients with posterior circulation large vessel occlusion (PC-LVO) who underwent successful mechanical thrombectomy (MT), this study retrospectively enrolled patients with PC-LVO who achieved successful recanalization between January 2019 and December 2022, and assessed their 3-month survival and functional outcomes. Using univariable and multivariable logistic regression, model-fitting analyses, and receiver operating characteristic (ROC) curves, it was found that the NIH Stroke Scale score at 24 hours postprocedure (NIHSS24h) independently predicted both poor functional outcomes and mortality in recanalized PC-LVO patients. Admission SBP and age were also significantly associated with prognosis. The results indicate that early vital signs may provide important insights into the risk of poor prognosis or death after MT in PC-LVO patients. These findings offer guidance for prognostic evaluation and patient selection for mechanical thrombectomy in posterior circulation stroke.

Journal of Craniofacial SurgeryVol. 37(3/4)
Jiangnan University (CN), Jiangsu University (CN), Soochow University (CN), First People's Hospital of Kunshan (CN), Gannan Medical University (CN), Guigang City People's Hospital (CN), Second Affiliated Hospital of Soochow University (CN), Shanghai Sunshine Rehabilitation Center (CN), Tongji Hospital (CN), Tianjin Medical University (CN), Wuxi Institute of Technology (CN)
Openalex Percentile: Top 53%
Acute Ischemic Stroke Management
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