Prediction of Respiratory Decompensation in Patients Receiving Home Mechanical Ventilation: Machine Learning Model Development and Validation Study

This study demonstrates the feasibility of predicting respiratory decompensation using data from HMV telemonitoring systems. Tree-based ensemble models, particularly random forests, provided the most balanced performance, while SHAP analysis offered clinically relevant insights. Although performance was moderate, the findings support further development of predictive tools to enable timely telemedical interventions. Limitations include sample size, missing physiological parameters, and a single-center design. Future research should expand to multicenter datasets and incorporate additional clinical variables to enhance model robustness and generalizability.

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Publication Details

Journal
JMIR Formative Research
Published
2025-11-21
DOI
https://doi.org/10.2196/78941
Primary Topic
Respiratory Support and Mechanisms
Type
article
Field-Weighted Citation Impact
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article

Prediction of Respiratory Decompensation in Patients Receiving Home Mechanical Ventilation: Machine Learning Model Development and Validation Study

Francesc López Seguí, Ignasi García-Olivé, Aída Selfa Muñoz, Marina Galdeano Lozano et al.
JMIR Formative Research
Respiratory Support and Mechanisms
article

Prediction of Respiratory Decompensation in Patients Receiving Home Mechanical Ventilation: Machine Learning Model Development and Validation Study

Francesc López Seguí, Ignasi García-Olivé, Aída Selfa Muñoz, Marina Galdeano Lozano, Antoni Rosell, Nerea Berbel Casado, Natalia Muñoz Moruno
article en

Abstract

This study demonstrates the feasibility of predicting respiratory decompensation using data from HMV telemonitoring systems. Tree-based ensemble models, particularly random forests, provided the most balanced performance, while SHAP analysis offered clinically relevant insights. Although performance was moderate, the findings support further development of predictive tools to enable timely telemedical interventions. Limitations include sample size, missing physiological parameters, and a single-center design. Future research should expand to multicenter datasets and incorporate additional clinical variables to enhance model robustness and generalizability.

JMIR Formative ResearchVol. 9
Universitat de Vic - Universitat Central de Catalunya (ES), Universitat Autònoma de Barcelona (ES), Universitat Pompeu Fabra (ES), Centre de Recerca en Economia Internacional (ES), Institut d'Investigació en Ciències de la Salut Germans Trias i Pujol (ES), Hospital Universitari Germans Trias i Pujol (ES)
Openalex Percentile: Top 49%
Respiratory Support and Mechanisms
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