Management of oropharyngeal squamous cell carcinoma: 2025 update
This article reviews the various exclusive or postoperative external radiotherapy and brachytherapy options for oropharyngeal squamous cell carcinoma. Dose levels, fractionation, and association with systemic treatments are presented. The need for neck node dissection following local treatment is discussed, as well as specificities for the management of p16-positive tumours. Guidelines for target volume selection and delineation are thoroughly elaborated.
Authors
- Ulrike Schick (ORCID: https://orcid.org/0000-0003-4950-9070)
- P. Boisselier (ORCID: https://orcid.org/0000-0003-0121-365X)
- F. Huguet (ORCID: https://orcid.org/0000-0002-5302-5784)
- Pierre‐Yves Blanchard (ORCID: https://orcid.org/0000-0003-1659-6868)
- Y. Pointreau (ORCID: https://orcid.org/0000-0002-2442-2879)
- L. Vieillevigne (ORCID: https://orcid.org/0000-0003-0680-7430)
- Cyrus Chargari (ORCID: https://orcid.org/0000-0003-0119-3695)
- Kévin Quintin
- V. Grégoire (ORCID: https://orcid.org/0000-0003-1491-8173)
- Philippe Giraud
- Thomas Leroy
Institutions
- Institut Gustave Roussy (FR)
- Sorbonne Université (FR)
- Assistance Publique – Hôpitaux de Paris (FR)
- Hôpital Européen Georges-Pompidou (FR)
- Centre Léon Bérard (FR)
- Hôpital Européen (FR)
- Pitié-Salpêtrière Hospital (FR)
- Centre Jean Bernard (FR)
- Groupe Hospitalier Cochin - Port-Royal, Hôtel-Dieu, Broca - La Collégiale (FR)
- Institut Claudius Regaud (FR)
- Centre Hospitalier Régional Universitaire de Brest (FR)
- Institut de Recherche en Cancérologie de Montpellier (FR)
- Centre Hospitalier de Valenciennes (FR)
- Hôpital Tenon (FR)
Publication Details
- Journal
- Cancer/Radiothérapie
- Published
- 2025-11-01
- DOI
- https://doi.org/10.1016/j.canrad.2025.104776
- Citations
- 1
- Primary Topic
- Head and Neck Cancer Studies
- Type
- article
- Field-Weighted Citation Impact
- 1.85