Bone Mineral Density Measurements and Fracture Prediction in the Very Elderly

Bone density decreases with age, increasing the risk of fragility fractures. Dual-energy X-ray absorptiometry (DEXA) scanning may be used to measure bone density and estimate this risk. Degenerative changes in the spine may decrease the accuracy of DEXA results. We present the clinical course of a 92-year-old woman with a diagnosis of osteopenia of the left femoral neck and a risk for fragility fracture that was previously below the threshold for treatment, who underwent routine follow-up bone density screening. The DEXA scan showed an increase in bone density at the lumbar spine. Within a week of this study, she experienced severe back pain rated eight to nine out of 10 without a precipitating event. The following day, a lumbar X-ray showed disk space narrowing at multiple levels, spondylolisthesis at L4/5, diffuse spondylosis, and a new compression fracture at T12. This case illustrates the challenges of preventing and treating low bone density in the very elderly.

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Publication Details

Journal
Cureus
Published
2025-11-21
DOI
https://doi.org/10.7759/cureus.97458
Primary Topic
Bone health and osteoporosis research
Type
article
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article

Bone Mineral Density Measurements and Fracture Prediction in the Very Elderly

Jeff Borenstein, Maryam Sharifi, Jarod DuVall, Jelena Maletkovic
Cureus
Bone health and osteoporosis research
article

Bone Mineral Density Measurements and Fracture Prediction in the Very Elderly

Jeff Borenstein, Maryam Sharifi, Jarod DuVall, Jelena Maletkovic
article en

Abstract

Bone density decreases with age, increasing the risk of fragility fractures. Dual-energy X-ray absorptiometry (DEXA) scanning may be used to measure bone density and estimate this risk. Degenerative changes in the spine may decrease the accuracy of DEXA results. We present the clinical course of a 92-year-old woman with a diagnosis of osteopenia of the left femoral neck and a risk for fragility fracture that was previously below the threshold for treatment, who underwent routine follow-up bone density screening. The DEXA scan showed an increase in bone density at the lumbar spine. Within a week of this study, she experienced severe back pain rated eight to nine out of 10 without a precipitating event. The following day, a lumbar X-ray showed disk space narrowing at multiple levels, spondylolisthesis at L4/5, diffuse spondylosis, and a new compression fracture at T12. This case illustrates the challenges of preventing and treating low bone density in the very elderly.

CureusVol. 17(11)
Los Angeles County Department of Health Services (US), University of California, Los Angeles (US)
Openalex Percentile: Top 55%
Bone health and osteoporosis research
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Bone Mineral Density Measurements and Fracture Prediction in the Very Elderly — Jeff Borenstein, Maryam Sharifi, et al. · Cureus (2025) | TGRS Research Map | TGRS