Multicenter 30-Year Data on the 4-Mg Intravenous Dexamethasone Suppression Test in the Diagnosis of Cushing Syndrome
The IVDST is a highly sensitive second-line diagnostic test for CS. False negative results occurred when IVDST is performed during an eucortisolemic phase of cyclic CD. The specificity of 87% emphasizes the importance of long-term follow-up of LPC. The small number of EAS cases is a major limitation in the use of IVDST to differentiate ACTH-dependent CS.
Authors
- John Burgess (ORCID: https://orcid.org/0000-0003-4748-9571)
- Chung Gang Jung (ORCID: https://orcid.org/0000-0002-1059-0257)
- Maresa M. Derbyshire
- Warrick J. Inder (ORCID: https://orcid.org/0000-0001-5078-4980)
- Nikola Marković (ORCID: https://orcid.org/0000-0003-4603-2721)
- Duncan J. Topliss (ORCID: https://orcid.org/0000-0003-4763-3385)
- Niyati Jauhar
- Reetu Gogna (ORCID: https://orcid.org/0000-0001-5704-6139)
- Daniel J. Bennett (ORCID: https://orcid.org/0000-0003-1041-3784)
Institutions
- University of Tasmania (AU)
- The University of Queensland (AU)
- The University of Melbourne (AU)
- Princess Alexandra Hospital (AU)
- Royal Hobart Hospital (AU)
- St Vincent's Hospital Melbourne (AU)
- Princess Alexandra Hospital (GB)
- Alfred Health (AU)
- Monash University (AU)
Publication Details
- Journal
- Journal of the Endocrine Society
- Published
- 2025-11-20
- DOI
- https://doi.org/10.1210/jendso/bvaf188
- Primary Topic
- Pituitary Gland Disorders and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Endocrine Society of Australia