Comprehensive map of axonal pathway activation as a function of subthalamic deep brain stimulation location and parameter settings
Evolving hypotheses suggest that activation of specific pathways may be related to the control of specific PD symptoms. This study provides detailed predictions on stimulation conditions that facilitate pathway selective DBS, as well as an interactive software tool that quantifies DBS pathway activation throughout the subthalamic region.
Authors
- Anneke M. Frankemolle‐Gilbert (ORCID: https://orcid.org/0000-0003-0724-8087)
- Angela M. Noecker (ORCID: https://orcid.org/0000-0001-5833-4263)
- Tjitske Heida (ORCID: https://orcid.org/0000-0002-8382-6291)
- Cameron C. McIntyre (ORCID: https://orcid.org/0000-0003-0932-854X)
Institutions
- Duke University (US)
- Duke University Hospital (US)
- University of Twente (NL)
Publication Details
- Journal
- Brain stimulation
- Published
- 2025-11-21
- DOI
- https://doi.org/10.1016/j.brs.2025.102992
- Primary Topic
- Neurological disorders and treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Institutes of Health