Identification and evaluation of a lipid-lowering small compound as a PCSK9 inhibitor
These findings demonstrate a small, non-statin compounds, and provide the potential alternative treatment approach for hyperlipidemic patients.
Authors
- Yong Zhang (ORCID: https://orcid.org/0000-0001-6316-2734)
- Xutong Wang (ORCID: https://orcid.org/0000-0002-4625-7659)
- Bin Sun (ORCID: https://orcid.org/0000-0003-2583-4493)
- Song Wang (ORCID: https://orcid.org/0000-0003-2757-6563)
- Jin Gao (ORCID: https://orcid.org/0000-0002-8019-9210)
- Yu Liu (ORCID: https://orcid.org/0000-0002-2346-740X)
- Xiaodong Fang (ORCID: https://orcid.org/0000-0001-7061-3337)
- Meng Sun (ORCID: https://orcid.org/0000-0002-7435-3752)
- Xin Liu (ORCID: https://orcid.org/0000-0002-4732-4403)
- Heng Liu (ORCID: https://orcid.org/0000-0001-6683-1462)
- Huimin Li (ORCID: https://orcid.org/0000-0001-6613-1159)
- Weina Han (ORCID: https://orcid.org/0000-0001-7241-1608)
- Jennifer Wang (ORCID: https://orcid.org/0000-0002-7897-007X)
- Run Xu
- Tong Zhao (ORCID: https://orcid.org/0009-0007-6734-3621)
- Zijia Dou
- Yiyang Li (ORCID: https://orcid.org/0009-0000-8881-0902)
- Yingying Hu (ORCID: https://orcid.org/0009-0002-5909-8252)
Institutions
- Harbin Medical University (CN)
- Université Laval (CA)
Publication Details
- Journal
- Journal of Advanced Research
- Published
- 2025-11-01
- DOI
- https://doi.org/10.1016/j.jare.2025.11.044
- Primary Topic
- Lipoproteins and Cardiovascular Health
- Type
- article
- Field-Weighted Citation Impact
- 0.00