Expert consensus on multidisciplinary collaboration in perioperative immunotherapy for hepatocellular carcinoma (2025 edition)
Abstract Immune checkpoint inhibitors (ICIs) have led to substantial advances in immunotherapy for hepatocellular carcinoma (HCC). Moreover, the use of ICI-based combination regimens for perioperative management of HCC has increased. To support clinicians in the rational, effective, and safe use of perioperative immunotherapy, the Hepatobiliary and Pancreatic Multidisciplinary Team Committee of the Chinese Chapter of the International Hepato-Pancreato-Biliary Association, the Hepatic Surgery Group of the Surgery Branch of the Chinese Medical Association, the General Surgery Branch of the Chinese Society of Geriatric Medicine, and the Editorial Board of Chinese Journal of Digestive Surgery convened a multidisciplinary expert panel to develop the Chinese Multidisciplinary Expert Consensus on Perioperative Immunotherapy for Hepatocellular Carcinoma (2025 Edition). This consensus focuses on the principles and clinical applications of ICI-based immunotherapy in the perioperative setting for HCC. Accordingly, this review summarizes clinical recommendations based on the latest research to guide healthcare professionals involved in HCC management.
Authors
- Yangxun Pan (ORCID: https://orcid.org/0000-0002-3887-5852)
- Leida Zhang (ORCID: https://orcid.org/0000-0002-7302-9184)
- Jiabei Wang (ORCID: https://orcid.org/0000-0002-4578-3817)
- Lianxin Liu (ORCID: https://orcid.org/0000-0002-3535-6467)
- Xiao Liang (ORCID: https://orcid.org/0000-0002-4158-4562)
- Shao‐Lai Zhou (ORCID: https://orcid.org/0000-0002-8526-5221)
- Jian Zhou (ORCID: https://orcid.org/0000-0002-8654-6439)
- Ying Zhu (ORCID: https://orcid.org/0000-0001-5247-6324)
- Hai-Su Dai (ORCID: https://orcid.org/0009-0005-8913-1721)
- Minshan Chen (ORCID: https://orcid.org/0000-0002-6741-7498)
- Ming Kuang (ORCID: https://orcid.org/0000-0003-0131-4848)
- Decai Yu (ORCID: https://orcid.org/0000-0002-3006-2531)
- Lun–Xiu Qin (ORCID: https://orcid.org/0000-0003-4805-8239)
- Jia Fan (ORCID: https://orcid.org/0000-0001-6386-1068)
- Chaoyi Yuan
- Qiang Wang (ORCID: https://orcid.org/0000-0001-6686-6630)
- Ledu Zhou (ORCID: https://orcid.org/0000-0003-0702-0429)
- Yilei Mao (ORCID: https://orcid.org/0000-0003-0449-4223)
- Zeyang Ding (ORCID: https://orcid.org/0000-0001-5826-0970)
- X Y Feng (ORCID: https://orcid.org/0000-0001-8826-6310)
- Kui Wang (ORCID: https://orcid.org/0000-0002-4756-9267)
- Xiaoping Chen (ORCID: https://orcid.org/0000-0001-8725-6591)
- Min Chen (ORCID: https://orcid.org/0000-0002-0093-9056)
- Yan He (ORCID: https://orcid.org/0000-0002-1260-4536)
- Jiahong Dong (ORCID: https://orcid.org/0000-0002-8002-9086)
- Hong Wu (ORCID: https://orcid.org/0000-0003-4789-8535)
- Minghao Sun (ORCID: https://orcid.org/0000-0002-1657-0740)
- J. Huo (ORCID: https://orcid.org/0009-0000-8594-8594)
- Bixiang Zhang
- Lin‐Lin Shen (ORCID: https://orcid.org/0000-0003-1976-8282)
- Bangde Xiang
Institutions
- University of Science and Technology of China (CN)
- Central South University (CN)
- Army Medical University (CN)
- Sun Yat-sen University (CN)
- Guangxi Medical University (CN)
- Second Military Medical University (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Sichuan University (CN)
- Fudan University (CN)
- Peking Union Medical College Hospital (CN)
- Sir Run Run Shaw Hospital (CN)
- West China Hospital of Sichuan University (CN)
- Nanjing Drum Tower Hospital (CN)
- Zhongshan Hospital (CN)
- The First Affiliated Hospital, Sun Yat-sen University (CN)
- Southwest Hospital (CN)
- Eastern Hepatobiliary Surgery Hospital (CN)
- Sun Yat-sen University Cancer Center (CN)
- Beijing Tsinghua Chang Gung Hospital (CN)
- Huashan Hospital (CN)
- Xiangya Hospital Central South University (CN)
- Tongji Hospital (CN)
- Huazhong University of Science and Technology (CN)
- Zhejiang University (CN)
- Tsinghua University (CN)
Publication Details
- Journal
- Oncology and Translational Medicine
- Published
- 2025-11-21
- DOI
- https://doi.org/10.1097/ot9.0000000000000122
- Primary Topic
- Cancer Immunotherapy and Biomarkers
- Type
- article
- Field-Weighted Citation Impact
- 0.00