Retrospective Analysis of Nail Changes and Comorbidities in Darier Disease

Nail changes were common in patients with DD and the first sign of disease in 20%. Nail examination was lacking in >1/4 of patients, demonstrating an opportunity for education. Patients with DD had high prevalence of comorbidities and cutaneous symptoms. Therefore, active monitoring for symptoms including burning, pain, and pruritus is important, especially in patients with baseline comorbidities.