Chemical constituents from the roots of <i>Morinda talmyi</i> (Rubiaceae)

Phytochemical investigation of the roots of <i>Morinda talmyi</i> (Pit.) Chantar. led to the isolation of eleven compounds. They consist of two previously undescribed anthraquinones, 3-hydroxy-1,2,5-trimethoxy-6-methylanthraquinone (<b>1</b>) and damnacanthol acetate (<b>2</b>), together with nine known compounds: 1-hydroxy-2-methyl-9,10-anthraquinone (<b>3</b>), soranjidiol (<b>4</b>), morindone (<b>5</b>), nordamnacanthal (<b>6</b>), lucidin (<b>7</b>), lucidin ω-methyl ether (<b>8</b>) lucidin ω-ethyl ether (<b>9</b>), damnacanthol (<b>10</b>) and lucidin 3-<i>O</i>-β-primeveroside (<b>11</b>). The structures of the isolated compounds were elucidated by thorough analysis of spectroscopic (IR, NMR) and spectrometric (MS) data. Compounds <b>1</b> and <b>2</b> were tested against eight bacterial strains. Only compound <b>2</b> exhibited weak activity against methicillin-resistant <i>Staphylococcus aureus</i> and <i>Staphylococcus aureus</i> (MIC = 128 µg/ml). This is the first phytochemical investigation of <i>M. talmyi</i>.

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Publication Details

Journal
Natural Product Research
Published
2025-11-21
DOI
https://doi.org/10.1080/14786419.2025.2588326
Citations
1
Primary Topic
Morinda citrifolia extract uses
Type
article
Field-Weighted Citation Impact
2.38
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article

Chemical constituents from the roots of Morinda talmyi (Rubiaceae)

Charupong Saengboonmee, Ratsami Lekphrom, Sophon Boonlue, Wasan Seemakram et al.
1 citations
Natural Product Research
Morinda citrifolia extract uses
2.38
article

Chemical constituents from the roots of Morinda talmyi (Rubiaceae)

Charupong Saengboonmee, Ratsami Lekphrom, Sophon Boonlue, Wasan Seemakram, Kanyarat Thithuan, Florian T. Schevenels, Phornnapa Saentao
article en
1 citations

Abstract

Phytochemical investigation of the roots of <i>Morinda talmyi</i> (Pit.) Chantar. led to the isolation of eleven compounds. They consist of two previously undescribed anthraquinones, 3-hydroxy-1,2,5-trimethoxy-6-methylanthraquinone (<b>1</b>) and damnacanthol acetate (<b>2</b>), together with nine known compounds: 1-hydroxy-2-methyl-9,10-anthraquinone (<b>3</b>), soranjidiol (<b>4</b>), morindone (<b>5</b>), nordamnacanthal (<b>6</b>), lucidin (<b>7</b>), lucidin ω-methyl ether (<b>8</b>) lucidin ω-ethyl ether (<b>9</b>), damnacanthol (<b>10</b>) and lucidin 3-<i>O</i>-β-primeveroside (<b>11</b>). The structures of the isolated compounds were elucidated by thorough analysis of spectroscopic (IR, NMR) and spectrometric (MS) data. Compounds <b>1</b> and <b>2</b> were tested against eight bacterial strains. Only compound <b>2</b> exhibited weak activity against methicillin-resistant <i>Staphylococcus aureus</i> and <i>Staphylococcus aureus</i> (MIC = 128 µg/ml). This is the first phytochemical investigation of <i>M. talmyi</i>.

Natural Product Research
Khon Kaen University (TH)
Openalex Percentile: Top 8%
Morinda citrifolia extract uses
2.38
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Chemical constituents from the roots of <i>Morinda talmyi</i> (Rubiaceae) — Charupong Saengboonmee, Ratsami Lekphrom, et al. · Natural Product Research (2025) | TGRS Research Map | TGRS