Chemical constituents from the roots of <i>Morinda talmyi</i> (Rubiaceae)
Phytochemical investigation of the roots of <i>Morinda talmyi</i> (Pit.) Chantar. led to the isolation of eleven compounds. They consist of two previously undescribed anthraquinones, 3-hydroxy-1,2,5-trimethoxy-6-methylanthraquinone (<b>1</b>) and damnacanthol acetate (<b>2</b>), together with nine known compounds: 1-hydroxy-2-methyl-9,10-anthraquinone (<b>3</b>), soranjidiol (<b>4</b>), morindone (<b>5</b>), nordamnacanthal (<b>6</b>), lucidin (<b>7</b>), lucidin ω-methyl ether (<b>8</b>) lucidin ω-ethyl ether (<b>9</b>), damnacanthol (<b>10</b>) and lucidin 3-<i>O</i>-β-primeveroside (<b>11</b>). The structures of the isolated compounds were elucidated by thorough analysis of spectroscopic (IR, NMR) and spectrometric (MS) data. Compounds <b>1</b> and <b>2</b> were tested against eight bacterial strains. Only compound <b>2</b> exhibited weak activity against methicillin-resistant <i>Staphylococcus aureus</i> and <i>Staphylococcus aureus</i> (MIC = 128 µg/ml). This is the first phytochemical investigation of <i>M. talmyi</i>.
Authors
- Charupong Saengboonmee (ORCID: https://orcid.org/0000-0003-1476-1129)
- Ratsami Lekphrom (ORCID: https://orcid.org/0000-0002-5841-544X)
- Sophon Boonlue (ORCID: https://orcid.org/0000-0002-2411-6863)
- Wasan Seemakram (ORCID: https://orcid.org/0000-0003-1211-5457)
- Kanyarat Thithuan (ORCID: https://orcid.org/0000-0003-2267-210X)
- Florian T. Schevenels
- Phornnapa Saentao
Institutions
- Khon Kaen University (TH)
Publication Details
- Journal
- Natural Product Research
- Published
- 2025-11-21
- DOI
- https://doi.org/10.1080/14786419.2025.2588326
- Citations
- 1
- Primary Topic
- Morinda citrifolia extract uses
- Type
- article
- Field-Weighted Citation Impact
- 2.38