Prospective Whole-Genome Sequencing to Identify Bacterial Transmission and Its Modifiers in Neonates
This cohort study involving infants in the NICU suggests that bacterial sequencing can accurately detect bacterial transmission events. Multivariate analysis suggests that the bacterial transmission risk on a NICU can be modified.
Authors
- Philipp Henneke (ORCID: https://orcid.org/0000-0001-7314-7984)
- Fabian Bürkin
- Martin Kuntz (ORCID: https://orcid.org/0000-0002-8231-2838)
- Tim Götting (ORCID: https://orcid.org/0000-0002-7753-3361)
- Tjibbe Donker (ORCID: https://orcid.org/0000-0001-9022-4240)
- Daniel Klotz (ORCID: https://orcid.org/0000-0003-2347-3866)
- Hans W. Fuchs (ORCID: https://orcid.org/0000-0003-1303-3699)
- Daniel E Jonas (ORCID: https://orcid.org/0000-0003-1964-8731)
- Sandra Reuter (ORCID: https://orcid.org/0000-0003-1672-5789)
- Martin Wolkewitz (ORCID: https://orcid.org/0000-0002-1268-5057)
- Thien Nguyen (ORCID: https://orcid.org/0000-0003-0376-1975)
- Christian K. Schneider (ORCID: https://orcid.org/0000-0002-6691-0045)
- Stefany Ayala-Montaño
- Iván Acevedo Monterrosa
Institutions
- University of Freiburg (DE)
- Bielefeld University (DE)
- University Medical Center Freiburg (DE)
- Klinikum Bielefeld (DE)
- Institute of Medical Microbiology and Hygiene (DE)
- Bethel University (US)
Publication Details
- Journal
- JAMA Network Open
- Published
- 2025-11-21
- DOI
- https://doi.org/10.1001/jamanetworkopen.2025.41409
- Primary Topic
- Bacterial Infections and Vaccines
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Deutsche Forschungsgemeinschaft
- Albert-Ludwigs-Universität Freiburg