Network analysis of cognition and function in Alzheimer’s disease: a cross-sectional study
AD progression features increasing network density and centrality shifts from executive-function-centered networks in mild AD to memory-centered networks in moderate-to-severe stages. Findings suggest stage-specific interventions: executive enhancement in mild AD and memory-focused approaches in advanced stages.
Authors
- Lingyun Hu (ORCID: https://orcid.org/0000-0002-1337-9123)
- Liandan Huang
- Sunke Chen
- Xianghe Zhu (ORCID: https://orcid.org/0000-0002-0302-1021)
- Ying Wang (ORCID: https://orcid.org/0000-0002-0388-4177)
- Lili Chen (ORCID: https://orcid.org/0000-0002-9965-8990)
- Yun Chen (ORCID: https://orcid.org/0000-0002-3746-594X)
- Yefu Wang (ORCID: https://orcid.org/0000-0001-5861-0205)
- Xinwu Ye
Institutions
- Wenzhou Medical University (CN)
- First Affiliated Hospital of Wenzhou Medical University (CN)
- Wenzhou Central Hospital (CN)
- Wenzhou City People's Hospital (CN)
Publication Details
- Journal
- Frontiers in Psychiatry
- Published
- 2025-11-21
- DOI
- https://doi.org/10.3389/fpsyt.2025.1661313
- Primary Topic
- Functional Brain Connectivity Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00