Posterior pole involvement as the presenting feature of varicella zoster virus- associated acute retinal necrosis in a young healthy man

Posterior pole involvement as the initial manifestation of ARN in immunocompetent individuals is uncommon. This case highlights the importance of recognizing atypical clinical phenotypes of ARN. While the intensive medical therapy did not prevent the loss of retinal tissue, it successfully halted the progression of the infection toward the fovea, thereby allowing the preservation of excellent final visual acuity. Although uncommon, macular involvement should be included in the differential diagnosis of viral retinopathies. Prompt diagnosis and appropriate antiviral therapy are critical to preserving visual function and preventing further complications.

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Publication Details

Journal
Journal of Ophthalmic Inflammation and Infection
Published
2025-11-21
DOI
https://doi.org/10.1186/s12348-025-00540-3
Primary Topic
Ocular Diseases and Behçet’s Syndrome
Type
article
Field-Weighted Citation Impact
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article

Posterior pole involvement as the presenting feature of varicella zoster virus- associated acute retinal necrosis in a young healthy man

Ravid Ben-Avi, Radgonde Amer
Journal of Ophthalmic Inflammation and Infection
Ocular Diseases and Behçet’s Syndrome
article

Posterior pole involvement as the presenting feature of varicella zoster virus- associated acute retinal necrosis in a young healthy man

Ravid Ben-Avi, Radgonde Amer
article en

Abstract

Posterior pole involvement as the initial manifestation of ARN in immunocompetent individuals is uncommon. This case highlights the importance of recognizing atypical clinical phenotypes of ARN. While the intensive medical therapy did not prevent the loss of retinal tissue, it successfully halted the progression of the infection toward the fovea, thereby allowing the preservation of excellent final visual acuity. Although uncommon, macular involvement should be included in the differential diagnosis of viral retinopathies. Prompt diagnosis and appropriate antiviral therapy are critical to preserving visual function and preventing further complications.

Journal of Ophthalmic Inflammation and InfectionVol. 15(1)
Hebrew University of Jerusalem (IL), Hadassah Medical Center (IL), Jerusalem Multidisciplinary College (IL)
Openalex Percentile: Top 50%
Ocular Diseases and Behçet’s Syndrome
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Posterior pole involvement as the presenting feature of varicella zoster virus- associated acute retinal necrosis in a young healthy man — Ravid Ben-Avi, Radgonde Amer · Journal of Ophthalmic Inflammation and Infection (2025) | TGRS Research Map | TGRS