3D bioprinted microneedle patches loaded with gambogic acid-iron-doxorubicin nanozymes for postoperative glioma in situ therapy via ferroptosis synergistic chemosensitization
MNs@GFD integrates localized drug release, BBB bypass, hypoxia relief and ferroptosis-mediated chemosensitization into a single platform, establishing a powerful and clinically translatable postoperative chemotherapeutic strategy against glioma.
Authors
- Yang Qiao (ORCID: https://orcid.org/0000-0002-3784-8334)
- Xianwen Wang (ORCID: https://orcid.org/0000-0002-7236-9267)
- Menghui Liu (ORCID: https://orcid.org/0000-0001-6021-4447)
- Zhonghuang Su (ORCID: https://orcid.org/0009-0006-4322-804X)
- Q. Cai
- Xingliang Dai (ORCID: https://orcid.org/0000-0002-0685-4766)
- Ziyi Li (ORCID: https://orcid.org/0000-0002-8298-0764)
- Sheng Cheng
- Peng Gao (ORCID: https://orcid.org/0009-0008-1896-5608)
Institutions
- Shangrao Normal University (CN)
- Anhui Medical University (CN)
- First Affiliated Hospital of Anhui Medical University (CN)
Publication Details
- Journal
- Journal of Nanobiotechnology
- Published
- 2025-11-21
- DOI
- https://doi.org/10.1186/s12951-025-03790-4
- Primary Topic
- Nanoplatforms for cancer theranostics
- Type
- article
- Field-Weighted Citation Impact
- 0.00