Identification and functional evaluation of cyclin-dependent kinase genes reveals that CDKB1;1 and CDKB2;2 contribute to the balance of mitosis and endoreduplication in Medicago truncatula nodule

Our study presents the comprehensive genome-wide analysis of the CDK gene family in M. truncatula, demonstrating that the essential role of CDKB1;1 and CDKB2;2 downregulation in symbiotic nitrogen fixation and endoreduplication offers new insights into cell cycle regulation in nodules. It also identifies potential targets for improving nitrogen fixation efficiency in legumes.

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Publication Details

Journal
BMC Plant Biology
Published
2025-11-21
DOI
https://doi.org/10.1186/s12870-025-07365-1
Primary Topic
Legume Nitrogen Fixing Symbiosis
Type
article
Field-Weighted Citation Impact
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article

Identification and functional evaluation of cyclin-dependent kinase genes reveals that CDKB1;1 and CDKB2;2 contribute to the balance of mitosis and endoreduplication in Medicago truncatula nodule

Huairong Pan, Rong Wang
BMC Plant Biology
Legume Nitrogen Fixing Symbiosis
article

Identification and functional evaluation of cyclin-dependent kinase genes reveals that CDKB1;1 and CDKB2;2 contribute to the balance of mitosis and endoreduplication in Medicago truncatula nodule

Huairong Pan, Rong Wang
article en

Abstract

Our study presents the comprehensive genome-wide analysis of the CDK gene family in M. truncatula, demonstrating that the essential role of CDKB1;1 and CDKB2;2 downregulation in symbiotic nitrogen fixation and endoreduplication offers new insights into cell cycle regulation in nodules. It also identifies potential targets for improving nitrogen fixation efficiency in legumes.

BMC Plant BiologyVol. 25(1)
Hunan University (CN)
Openalex Percentile: Top 74%
Legume Nitrogen Fixing Symbiosis
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