Real-world outcomes of anthracycline and taxane-based perioperative breast cancer therapy using the Japanese electronic medical record database
RDI was high in all groups. Clinicians should be cautious when administering AC q3w therapy owing to the high likelihood of patients developing Grade 4 neutropenia. For TC, a slightly lower pegfilgrastim administration rate and >20% Grade 4 neutropenia suggest the need for appropriate pegfilgrastim use.
Authors
- Fuyuhiko Motoi (ORCID: https://orcid.org/0000-0001-7601-8395)
- Tomoko Kazato
- Masaaki Kawai (ORCID: https://orcid.org/0000-0003-1383-0487)
- Sayaka Matsuura
- Wakana Kiyosaki
Institutions
- Yamagata University (JP)
- Toppan (Japan) (JP)
Publication Details
- Journal
- Japanese Journal of Clinical Oncology
- Published
- 2025-11-21
- DOI
- https://doi.org/10.1093/jjco/hyaf177
- Primary Topic
- Neutropenia and Cancer Infections
- Type
- article
- Field-Weighted Citation Impact
- 0.00