Immune checkpoint inhibitor-associated hypothyroidism, macular rash and adrenal insufficiency: case report and review of the literature
This is a typical case of endocrine irAEs caused by ICIs, and the patient's macular rash may also be related to ICIs. For patients treated with ICIs, preventive monitoring of symptoms of irAEs and related hormones is crucial for timely diagnosis, treatment, and even prevention of endocrine crisis.
Authors
- Lixin Guo (ORCID: https://orcid.org/0000-0001-6863-1798)
- Feng-shou Yi
- Peng George Wang (ORCID: https://orcid.org/0000-0003-3335-6794)
- Xingping Wu (ORCID: https://orcid.org/0000-0002-3182-688X)
- Zhong-qing Mou
- Shengli Wu (ORCID: https://orcid.org/0000-0003-2008-1736)
Institutions
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Karamay Central Hospital (CN)
- Karamay Central Hospital of Xinjiang (CN)
Publication Details
- Journal
- BMC Endocrine Disorders
- Published
- 2025-11-21
- DOI
- https://doi.org/10.1186/s12902-025-02089-7
- Citations
- 1
- Primary Topic
- Cancer Immunotherapy and Biomarkers
- Type
- article
- Field-Weighted Citation Impact
- 1.05