A clinical presentation of rhino-orbito-cerebral mucormycosis in a patient with aplastic anemia: a case report

This case highlights the diagnostic and therapeutic challenges in managing mucormycosis in patients with hematological disorders. A key factor contributing to the unfavorable outcome was the prolonged interval between symptom onset and rhino-orbito-cerebral mucormycosis diagnosis. Physicians should consider invasive fungal infections in all immunocompromised patients, particularly those with aplastic anemia, when they present with facial soft tissue infections.

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Publication Details

Journal
Journal of Medical Case Reports
Published
2025-11-21
DOI
https://doi.org/10.1186/s13256-025-05616-1
Primary Topic
Antifungal resistance and susceptibility
Type
article
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article

A clinical presentation of rhino-orbito-cerebral mucormycosis in a patient with aplastic anemia: a case report

Mohammadreza Salehi, Faeze Salahshour, Tahere Yousefi, Kamran Roudini et al.
Journal of Medical Case Reports
Antifungal resistance and susceptibility
article

A clinical presentation of rhino-orbito-cerebral mucormycosis in a patient with aplastic anemia: a case report

Mohammadreza Salehi, Faeze Salahshour, Tahere Yousefi, Kamran Roudini, Sogol Alikarami, Pooya Javaherchian, Masoud Jafarinaasab
article en

Abstract

This case highlights the diagnostic and therapeutic challenges in managing mucormycosis in patients with hematological disorders. A key factor contributing to the unfavorable outcome was the prolonged interval between symptom onset and rhino-orbito-cerebral mucormycosis diagnosis. Physicians should consider invasive fungal infections in all immunocompromised patients, particularly those with aplastic anemia, when they present with facial soft tissue infections.

Journal of Medical Case ReportsVol. 19(1)
Iran University of Medical Sciences (IR), Shahid Sadoughi University of Medical Sciences and Health Services (IR), Imam Khomeini Hospital (IR), Pharmaceutical Sciences Research Center, Tehran University of Medical Sciences (IR)
Openalex Percentile: Top 58%
Antifungal resistance and susceptibility
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A clinical presentation of rhino-orbito-cerebral mucormycosis in a patient with aplastic anemia: a case report — Mohammadreza Salehi, Faeze Salahshour, et al. · Journal of Medical Case Reports (2025) | TGRS Research Map | TGRS