Regioselective C-Arylation of Functionalized Nitroalkanes with Furan, Thiophene, and Substituted Thiophenes
A user-friendly, highly regioselective C-arylation of nitroalkanes with thiophenes and furan, employing a fascinating one-pot cascade process, has been developed. The formal C-H activation proceeds under mild conditions and follows a well-understood reaction mechanism supported by both experimental data and thorough theoretical investigation.
Authors
- Tomáš Malatinský
- Miroslav Medveď (ORCID: https://orcid.org/0000-0001-8599-1031)
- Pavol Jakubec (ORCID: https://orcid.org/0000-0001-8872-3817)
- Katarína Ráchel Detková
- Šimon Budzák (ORCID: https://orcid.org/0000-0003-4811-8342)
- Marek Cigáň (ORCID: https://orcid.org/0000-0001-7734-626X)
- Juraj Filo (ORCID: https://orcid.org/0000-0002-3995-2565)
- Kristína Jakubcová
Institutions
- Slovak University of Technology in Bratislava (SK)
- Regional Centre of Advanced Technologies and Materials (CZ)
- Matej Bel University (SK)
- Palacký University Olomouc (CZ)
- Comenius University Bratislava (SK)
Publication Details
- Journal
- The Journal of Organic Chemistry
- Published
- 2025-11-21
- DOI
- https://doi.org/10.1021/acs.joc.5c02410
- Primary Topic
- Catalytic C–H Functionalization Methods
- Type
- article
- Field-Weighted Citation Impact
- 0.00