Comparative meta-transcriptomic analysis of nasal and anal microbiota in respiratory syncytial virus mono and co-infected children

Our study revealed that multi-infected RSV subjects revealed the highest difference in microbial composition of the nasal microbiota compared to single infected and control subjects. Whether the observed microbiome difference is related to increased disease severity is yet to be explored in future studies. Moreover, the potential use of Lactobacillus and Bacteroides as probiotics for the treatment and prevention of RSV infection should be explored in future research.