Clonal identification and homology differentiate primary central nervous system lymphoma from non-central nervous system lymphoplasmacytic lymphoma: a case report
It was revealed that the lymphoma cells of both lymphoplasmacytic lymphoma/Waldenström macroglobulinemia and primary central nervous system lymphoma derived from a common cell possessing MYD88. The utility of adding chemotherapy for low-grade lymphoma in addition to therapy for primary central nervous system lymphoma is not clear. While lymphoplasmacytic lymphoma is a low-grade lymphoma that does not always require chemotherapy, combining treatment for lymphoplasmacytic lymphoma and primary central nervous system lymphoma may contribute to the effectiveness of both treatments.
Authors
- Daigo Akahane (ORCID: https://orcid.org/0000-0002-9295-1465)
- Tamiko Suguro
- Nahoko Furuya
- Seiichi Okabe (ORCID: https://orcid.org/0000-0002-2727-658X)
- Seiichiro Katagiri (ORCID: https://orcid.org/0000-0002-3031-9990)
- Shinjiro Fukami
- Toshitaka Nagao (ORCID: https://orcid.org/0000-0003-2075-9738)
- Moritaka Gotoh
- Yuko Tanaka (ORCID: https://orcid.org/0000-0002-1114-8188)
- Mitsuru Moriyama (ORCID: https://orcid.org/0000-0003-2105-1432)
- Hiroaki Fujimoto (ORCID: https://orcid.org/0000-0001-9419-3189)
- Akihiko Gotoh (ORCID: https://orcid.org/0000-0002-8608-4393)
- Naoya Nakamura (ORCID: https://orcid.org/0000-0003-4332-5254)
- Maki Tanigawa
- Michiyo Asano
- Akiko Yamada
- Michihiro Kohno
- S Ohtsuki
- Jun Matubayashi
- Seiichiro Yosizawa
Institutions
- Tokai University (JP)
- Tokyo Medical University (JP)
Publication Details
- Journal
- Journal of Medical Case Reports
- Published
- 2025-11-21
- DOI
- https://doi.org/10.1186/s13256-025-05677-2
- Primary Topic
- CNS Lymphoma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00