Histone-based liquid biopsy discriminates between myelodysplastic syndrome and solid malignancies
Overall, we identified circulating histone signatures able to discriminate between solid and MDS, using a rapid and non-invasive imaging technology, which may improve patient diagnosis.
Authors
- Ilina Micheva (ORCID: https://orcid.org/0000-0003-2641-8635)
- Rostislav Manev
- Dragomir Svetozarov Stoyanov (ORCID: https://orcid.org/0000-0003-2064-9475)
- Merlin Efraim (ORCID: https://orcid.org/0000-0001-6570-6643)
- Nikolay Conev (ORCID: https://orcid.org/0000-0001-5267-0354)
- Desislava K. Tsoneva (ORCID: https://orcid.org/0000-0002-8141-2482)
- Maria Teneva
- Trifon Chervenkov (ORCID: https://orcid.org/0000-0002-4964-1795)
- Manlio Vinciguerra (ORCID: https://orcid.org/0000-0002-1768-3894)
- Jan Červený (ORCID: https://orcid.org/0000-0002-5046-3105)
- Diana Búzová (ORCID: https://orcid.org/0000-0002-8513-0546)
- Tommaso Mazza (ORCID: https://orcid.org/0000-0003-0434-8533)
- Salvatore Daniele Bianco (ORCID: https://orcid.org/0000-0001-7466-9741)
- Igor Resnick
- Nikol Daskalova
Institutions
- Medical University of Varna (BG)
- Casa Sollievo della Sofferenza (IT)
- Agostino Gemelli University Polyclinic (IT)
- University Hospital St. Marina (BG)
- Czech Academy of Sciences, Global Change Research Institute (CZ)
Publication Details
- Journal
- Clinical Epigenetics
- Published
- 2025-11-21
- DOI
- https://doi.org/10.1186/s13148-025-01995-w
- Primary Topic
- Acute Myeloid Leukemia Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Bulgarian National Science Fund