Immunotherapy and impact on tissue reservoirs

Immunotherapies represent a promising path toward an HIV cure, however their ability to target viral reservoirs within tissues represents a major challenge. Combination approaches leveraging multiple immunotherapy strategies, and other agents to reduce the HIV reservoir will likely be required to achieve viral control in the absence of antiretroviral therapy.

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Publication Details

Journal
Current Opinion in HIV and AIDS
Published
2025-11-21
DOI
https://doi.org/10.1097/coh.0000000000000996
Primary Topic
HIV Research and Treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Immunotherapy and impact on tissue reservoirs

Rachel D. Pascoe, Michael A. Moso, Thomas A. Angelovich, Hannah A. D. King et al.
Current Opinion in HIV and AIDS
HIV Research and Treatment
article

Immunotherapy and impact on tissue reservoirs

Rachel D. Pascoe, Michael A. Moso, Thomas A. Angelovich, Hannah A. D. King, Sharon R. Lewin, Melissa J. Churchill
article en

Abstract

Immunotherapies represent a promising path toward an HIV cure, however their ability to target viral reservoirs within tissues represents a major challenge. Combination approaches leveraging multiple immunotherapy strategies, and other agents to reduce the HIV reservoir will likely be required to achieve viral control in the absence of antiretroviral therapy.

Current Opinion in HIV and AIDSVol. 21(1)
The Royal Melbourne Hospital (AU), Burnet Institute (AU), The University of Melbourne (AU), Aarhus University Hospital (DK), Peter Doherty Institute (AU), Lifenet Health (US), RMIT Europe (ES), Monash University (AU)
Openalex Percentile: Top 62%
HIV Research and Treatment
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Immunotherapy and impact on tissue reservoirs — Rachel D. Pascoe, Michael A. Moso, et al. · Current Opinion in HIV and AIDS (2025) | TGRS Research Map | TGRS