Acute and Chronic Effects of a High-Intensity Interval Training Shock Microcycle on Cell-Free DNA: A Randomized Controlled Trial

cfDNA is a reliable marker for detecting acute exercise-induced stress. However, the potential of cfDNA for detecting chronic adaptations in short-term, high-intensity interval training settings, such as a HIIT shock cycle, appears limited thus far. Trial registration clinicaltrials.gov, NCT05067426. Registered 05 October 2021-Retrospectively registered, https://clinicaltrials.gov/ct2/show/NCT05067426 .

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Publication Details

Journal
Sports Medicine - Open
Published
2025-11-21
DOI
https://doi.org/10.1186/s40798-025-00923-9
Primary Topic
Genetics and Physical Performance
Type
article
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article

Acute and Chronic Effects of a High-Intensity Interval Training Shock Microcycle on Cell-Free DNA: A Randomized Controlled Trial

Aleksandar Tomaskovic, Elmo W. I. Neuberger, Nils Haller, Thomas Stöggl et al.
Sports Medicine - Open
Genetics and Physical Performance
article

Acute and Chronic Effects of a High-Intensity Interval Training Shock Microcycle on Cell-Free DNA: A Randomized Controlled Trial

Aleksandar Tomaskovic, Elmo W. I. Neuberger, Nils Haller, Thomas Stöggl, Tilmann Strepp, Perikles Simon
article en

Abstract

cfDNA is a reliable marker for detecting acute exercise-induced stress. However, the potential of cfDNA for detecting chronic adaptations in short-term, high-intensity interval training settings, such as a HIIT shock cycle, appears limited thus far. Trial registration clinicaltrials.gov, NCT05067426. Registered 05 October 2021-Retrospectively registered, https://clinicaltrials.gov/ct2/show/NCT05067426 .

Sports Medicine - OpenVol. 11(1)
University of Salzburg (AT), Johannes Gutenberg University Mainz (DE), Universitätsmedizin Göttingen (DE), Unfallkrankenhaus Salzburg (AT), University of Göttingen (DE)
Openalex Percentile: Top 62%
Genetics and Physical Performance
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Acute and Chronic Effects of a High-Intensity Interval Training Shock Microcycle on Cell-Free DNA: A Randomized Controlled Trial — Aleksandar Tomaskovic, Elmo W. I. Neuberger, et al. · Sports Medicine - Open (2025) | TGRS Research Map | TGRS