Genomic monitoring and tracking of mpox virus clade Ib in Burundi between july to september 2024

In summary, we identify sustained circulation of clade Ib MPXV in Burundi, most likely after several different introductions from the bordering province of South Kivu-DRC. The virus has acquired several additional APOBEC-3 mediated mutations, in line with reported evidence of ongoing human-to-human transmission.

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Publication Details

Journal
Communications Medicine
Published
2025-11-21
DOI
https://doi.org/10.1038/s43856-025-01199-6
Primary Topic
Poxvirus research and outbreaks
Type
article
Field-Weighted Citation Impact
0.00
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article

Genomic monitoring and tracking of mpox virus clade Ib in Burundi between july to september 2024

Hayley Cassidy, Saria Otani, Marion Koopmans, Idrissa Diawara et al.
Communications Medicine
Poxvirus research and outbreaks
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Genomic monitoring and tracking of mpox virus clade Ib in Burundi between july to september 2024

Hayley Cassidy, Saria Otani, Marion Koopmans, Idrissa Diawara, Alexis Niyomwungere, Frank M. Aarestrup, Leonard Schuele, Joseph Nyandwi, Celestin Nibogora, Cassien Nduwimana, Bas B. Oude Munnink, David F. Nieuwenhuijse, Théogène Ihorimbere, Denis Niyomwungere, Marjan Boter, Néhémie Nzoyikorera, N A Armstrong, Dionis Nizigiyimana, Marie Noelle Uwineza
article en

Abstract

In summary, we identify sustained circulation of clade Ib MPXV in Burundi, most likely after several different introductions from the bordering province of South Kivu-DRC. The virus has acquired several additional APOBEC-3 mediated mutations, in line with reported evidence of ongoing human-to-human transmission.

Communications MedicineVol. 5(1)
Université du Burundi (BI), Republic of Burundi (BI), Erasmus MC (NL), Ministère de la Santé Publique (BI), Université Mohammed VI des Sciences et de la Santé (MA), National Institute of Public Health (LA), Technical University of Denmark (DK), University of Hassan II Casablanca (MA)
Openalex Percentile: Top 62%
Poxvirus research and outbreaks
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