A high signal-to-noise ratio and high-frequency seesaw cantilever for high-speed atomic force microscopy

The cantilever mediates tip-sample interaction detection in all atomic force microscopes (AFMs). Canonical cantilevers are beams, where length, width, and thickness define the physical properties such as stiffness and resonant frequency, that also mediate laser-reflection to report on cantilever deflection. High-speed AFM (HS-AFM) demands miniaturized cantilevers that are soft and fast, but miniaturized beams reduce laser signal quality. Here, we present a seesaw cantilever with a rigid reflective board oscillating over torsional hinges separating the laser-reflective and mechanical functions. Finite element analysis verified the seesaw mechanism. The board can be optimized for laser-reflection and the shortened distance between tip and hinges enhances the angular sensitivity, while the stiffness is tunable via the hinge dimensions. We detail seesaw cantilever design, fabrication, tip addition, physical equations, and sub-molecular imaging of biological samples. We propose that seesaw cantilevers offer a promising alternative to traditional beam cantilevers for diverse AFM applications.

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Publication Details

Journal
Nature Communications
Published
2025-11-21
DOI
https://doi.org/10.1038/s41467-025-65240-x
Citations
2
Primary Topic
Force Microscopy Techniques and Applications
Type
article
Field-Weighted Citation Impact
2.49

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article

A high signal-to-noise ratio and high-frequency seesaw cantilever for high-speed atomic force microscopy

Simon Scheuring, Linlin Li, Atsushi Miyagi
2 citations
Nature Communications
Force Microscopy Techniques and Applications
2.49
article

A high signal-to-noise ratio and high-frequency seesaw cantilever for high-speed atomic force microscopy

Simon Scheuring, Linlin Li, Atsushi Miyagi
article en
2 citations

Abstract

The cantilever mediates tip-sample interaction detection in all atomic force microscopes (AFMs). Canonical cantilevers are beams, where length, width, and thickness define the physical properties such as stiffness and resonant frequency, that also mediate laser-reflection to report on cantilever deflection. High-speed AFM (HS-AFM) demands miniaturized cantilevers that are soft and fast, but miniaturized beams reduce laser signal quality. Here, we present a seesaw cantilever with a rigid reflective board oscillating over torsional hinges separating the laser-reflective and mechanical functions. Finite element analysis verified the seesaw mechanism. The board can be optimized for laser-reflection and the shortened distance between tip and hinges enhances the angular sensitivity, while the stiffness is tunable via the hinge dimensions. We detail seesaw cantilever design, fabrication, tip addition, physical equations, and sub-molecular imaging of biological samples. We propose that seesaw cantilevers offer a promising alternative to traditional beam cantilevers for diverse AFM applications.

Nature CommunicationsVol. 16(1)
Cornell University (US), Weill Cornell Medicine (US)
City University of New York, Advanced Storage Research Consortium, National Institute of Neurological Disorders and Stroke
Openalex Percentile: Top 9%
Force Microscopy Techniques and Applications
2.49
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