Hybrid nanofluid-based targeted drug delivery system for tumor therapy under magnetic and thermal control

This research investigates the dynamic behavior of unsteady squeezing flow involving a non-Newtonian nanofluid permeating through a porous medium confined between two parallel plates, with particular emphasis on the influence of Hall currents and an internal heat source. The governing partial differential equations are reformulated into nonlinear ordinary differential equations using similarity transformations. Analytical solutions are derived employing advanced techniques such as the Homotopy Perturbation Method, Akbari-Ganji Method, and numerical solutions via the fourth-order Runge-Kutta method (RK4), all implemented in Python with the aid of its computational capabilities. Notably, the SymPy library is utilized to handle symbolic computations. The study provides a comprehensive analysis of axial velocity, radial velocity, temperature, and nanoparticle concentration distributions under varying parameter conditions. Key findings indicate that an increase in the Prandtl number or heat source intensity elevates the temperature, while a higher thermophoretic parameter results in reduced nanoparticle concentration. The minimum errors for velocity, temperature, and concentration are 2×10<sup>-8</sup>, while that for radial velocity is 1×10<sup>-8</sup>. The findings have potential applications in various fields such as industry, biology, and biomedical engineering (including drug delivery and photothermal therapy).

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Publication Details

Journal
Scientific Reports
Published
2025-11-21
DOI
https://doi.org/10.1038/s41598-025-25372-y
Citations
1
Primary Topic
Nanofluid Flow and Heat Transfer
Type
article
Field-Weighted Citation Impact
0.67
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article

Hybrid nanofluid-based targeted drug delivery system for tumor therapy under magnetic and thermal control

Pooriya Majidi Zar, Vooria Majidi Zar
1 citations
Scientific Reports
Nanofluid Flow and Heat Transfer
0.67
article

Hybrid nanofluid-based targeted drug delivery system for tumor therapy under magnetic and thermal control

Pooriya Majidi Zar, Vooria Majidi Zar
article en
1 citations

Abstract

This research investigates the dynamic behavior of unsteady squeezing flow involving a non-Newtonian nanofluid permeating through a porous medium confined between two parallel plates, with particular emphasis on the influence of Hall currents and an internal heat source. The governing partial differential equations are reformulated into nonlinear ordinary differential equations using similarity transformations. Analytical solutions are derived employing advanced techniques such as the Homotopy Perturbation Method, Akbari-Ganji Method, and numerical solutions via the fourth-order Runge-Kutta method (RK4), all implemented in Python with the aid of its computational capabilities. Notably, the SymPy library is utilized to handle symbolic computations. The study provides a comprehensive analysis of axial velocity, radial velocity, temperature, and nanoparticle concentration distributions under varying parameter conditions. Key findings indicate that an increase in the Prandtl number or heat source intensity elevates the temperature, while a higher thermophoretic parameter results in reduced nanoparticle concentration. The minimum errors for velocity, temperature, and concentration are 2×10<sup>-8</sup>, while that for radial velocity is 1×10<sup>-8</sup>. The findings have potential applications in various fields such as industry, biology, and biomedical engineering (including drug delivery and photothermal therapy).

Scientific ReportsVol. 15(1)
Islamic Azad University, Tehran (IR), Tehran University of Medical Sciences (IR)
Openalex Percentile: Top 24%
Nanofluid Flow and Heat Transfer
0.67
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Hybrid nanofluid-based targeted drug delivery system for tumor therapy under magnetic and thermal control — Pooriya Majidi Zar, Vooria Majidi Zar · Scientific Reports (2025) | TGRS Research Map | TGRS