Text-Guided Inpainting for Aesthetic Prediction in Orthofacial Surgery: A Patient-Centered AI Approach
<i>Background and Objectives:</i> Artificial intelligence (AI) is increasingly impacting medicine by improving healthcare delivery and simplifying diagnostic and therapeutic processes. Text-guided inpainting is a promising tool in orthofacial surgery for generating ideal, patient-specific facial profiles. <i>Materials and Methods:</i> A total of 89 patients with dentofacial deformities (DFDs) were evaluated. The DALL-E2 platform was used to generate profilometric transformations based on textual prompts. The resulting images were assessed by three groups: patients, expert surgeons, and the general population. <i>Results:</i> A total of 94% of surgeons, 85% of the general population, and 79% of patients rated the AI-modified profiles as more aesthetically pleasing than the originals. The prompt inspired by runway models had the highest agreement across groups. <i>Conclusions:</i> Generative AI and text-guided inpainting show potential for enhancing aesthetic planning in orthofacial surgery, offering personalized treatment paths and aiding virtual surgical planning.
Authors
- Vincenzo Abbate (ORCID: https://orcid.org/0000-0002-7905-0531)
- Giovanni Dell’Aversana Orabona (ORCID: https://orcid.org/0000-0001-6479-6130)
- Riccardo Nocini (ORCID: https://orcid.org/0000-0001-5086-4390)
- Daniela Pacella (ORCID: https://orcid.org/0000-0003-2343-5069)
- Stefania Troise (ORCID: https://orcid.org/0000-0001-8421-0328)
- Cristiano Russo (ORCID: https://orcid.org/0000-0002-8732-1733)
- Cristian Tommasino (ORCID: https://orcid.org/0000-0001-9763-8745)
- Luigi Angelo Vaira (ORCID: https://orcid.org/0000-0002-7789-145X)
- Gabriele Canzi (ORCID: https://orcid.org/0000-0002-2513-369X)
- Antonio M. Rinaldi (ORCID: https://orcid.org/0000-0001-7003-4781)
- Emanuele Carraturo (ORCID: https://orcid.org/0000-0001-6463-5118)
- Giorgio Novelli (ORCID: https://orcid.org/0000-0003-2357-6726)
- Domenico Benfenati (ORCID: https://orcid.org/0009-0008-5825-8043)
- Sara Tramontano (ORCID: https://orcid.org/0009-0006-9761-5651)
Institutions
- University of Verona (IT)
- University of Sassari (IT)
- Azienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda (IT)
- Azienda Ospedaliera San Gerardo (IT)
- Federico II University Hospital (IT)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
- University of Naples Federico II (IT)
Publication Details
- Journal
- Medicina
- Published
- 2025-11-21
- DOI
- https://doi.org/10.3390/medicina61122075
- Citations
- 1
- Primary Topic
- Orthodontics and Dentofacial Orthopedics
- Type
- article
- Field-Weighted Citation Impact
- 1.68