Role of pain and anxiety in mediating relationships between donation history and vasovagal reaction symptoms in blood donors in England
Our findings suggest that differences in venipuncture pain and donation anxiety do not primarily explain differences in VVR symptoms by blood donation history. While intervening on pain and anxiety may fail to equalize symptom disparities linked to donation history, interventions may reduce VVR burden in donors without VVR histories.
Authors
- David J. Roberts (ORCID: https://orcid.org/0000-0003-0648-6585)
- Angela Wood (ORCID: https://orcid.org/0000-0002-7937-304X)
- Emanuele Di Angelantonio (ORCID: https://orcid.org/0000-0001-8776-6719)
- Eamonn Ferguson (ORCID: https://orcid.org/0000-0002-7678-1451)
- Nathalie Kingston (ORCID: https://orcid.org/0000-0002-9190-2231)
- Philippe T. Gilchrist (ORCID: https://orcid.org/0000-0001-5036-3369)
- Barbara Masser (ORCID: https://orcid.org/0000-0001-9385-6497)
- Yaning Wu (ORCID: https://orcid.org/0009-0003-7698-4675)
- Lois G. Kim (ORCID: https://orcid.org/0000-0002-4552-3820)
- Matthew R. Walker
- Stephen Kaptoge
Institutions
- National Health Service (GB)
- NHS Blood and Transplant (GB)
- University of Nottingham (GB)
- The University of Queensland (AU)
- Australian Red Cross Lifeblood (AU)
- University of Cambridge (GB)
- John Radcliffe Hospital (GB)
- British Heart Foundation (GB)
- National Institute for Health and Care Excellence (GB)
- National Institute for Health and Care Research (GB)
- University of Oxford (GB)
- Human Technopole (IT)
- Arthritis UK (GB)
- Macquarie University (AU)
Publication Details
- Journal
- Transfusion
- Published
- 2025-11-21
- DOI
- https://doi.org/10.1111/trf.70004
- Primary Topic
- Blood donation and transfusion practices
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- NHS Blood and Transplant
- Wellcome Trust
- Scottish Government
- National Institute for Health and Care Research
- British Heart Foundation
- Department of Health and Social Care
- University of Cambridge
- Public Health Agency
- Chief Scientist Office, Scottish Government Health and Social Care Directorate
- NIHR BioResource
- Medical Research Council
- Engineering and Physical Sciences Research Council
- Economic and Social Research Council
- Health and Social Care Research and Development Division