Enhancing cardiac disease prediction with explainable bidirectional LSTM

Cardiovascular disorders (heart diseases) are the most prevalent cause of death on a global scale. So early detection and classification increase the likelihood of survival. In the context of machine learning techniques, there is always a need for an accurate and explainable predictive model for detecting various diseases, such as cardiac disorders. The work carried out in this paper stacks bidirectional long short-term memory with deep learning to propose two models. The first model is used to detect cardiac disease with a binary label classification, while the second one classifies cardiac disease, which is a multi-label classification problem. Bidirectional LSTM is used as an approximate algorithm for feature extraction. Deep learning is used for classification purposes. The proposed models are trained and validated over the PTB-XL dataset. The performance of these models is evaluated and compared against state-of-the-art methods. The comparison shows the proposed model outperforms other methods in terms of accuracy, precision, f1-score, and recall. SHAP is used to make these models explainable, which in turn helps to annotate different diseases on the ECG report.

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Publication Details

Journal
Scientific Reports
Published
2025-11-21
DOI
https://doi.org/10.1038/s41598-025-25071-8
Primary Topic
ECG Monitoring and Analysis
Type
article
Field-Weighted Citation Impact
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article

Enhancing cardiac disease prediction with explainable bidirectional LSTM

Subhra Debdas, Korhan Cengiz, Ranjan K. Dash, Nitai Pal et al.
Scientific Reports
ECG Monitoring and Analysis
article

Enhancing cardiac disease prediction with explainable bidirectional LSTM

Subhra Debdas, Korhan Cengiz, Ranjan K. Dash, Nitai Pal, Swati Lipsa, Pankaj Kumar
article en

Abstract

Cardiovascular disorders (heart diseases) are the most prevalent cause of death on a global scale. So early detection and classification increase the likelihood of survival. In the context of machine learning techniques, there is always a need for an accurate and explainable predictive model for detecting various diseases, such as cardiac disorders. The work carried out in this paper stacks bidirectional long short-term memory with deep learning to propose two models. The first model is used to detect cardiac disease with a binary label classification, while the second one classifies cardiac disease, which is a multi-label classification problem. Bidirectional LSTM is used as an approximate algorithm for feature extraction. Deep learning is used for classification purposes. The proposed models are trained and validated over the PTB-XL dataset. The performance of these models is evaluated and compared against state-of-the-art methods. The comparison shows the proposed model outperforms other methods in terms of accuracy, precision, f1-score, and recall. SHAP is used to make these models explainable, which in turn helps to annotate different diseases on the ECG report.

Scientific ReportsVol. 15(1)
Odisha University of Agriculture and Technology (IN), Manipal Academy of Higher Education (IN), Indian Institute of Technology Dhanbad (IN), Istinye University (TR), Odisha University of Technology and Research, KIIT University (IN)
Openalex Percentile: Top 47%
ECG Monitoring and Analysis
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Enhancing cardiac disease prediction with explainable bidirectional LSTM — Subhra Debdas, Korhan Cengiz, et al. · Scientific Reports (2025) | TGRS Research Map | TGRS