Inverse Association Between METS-IR and Lung Cancer Risk: The Role of BMI in a Nationwide Korean Cohort

In this nationwide cohort study, we observed a significant inverse association between METS-IR and lung cancer risk. However, METS-IR showed limitations in fully explaining lung cancer risk based on insulin resistance alone. These findings highlight the need for future studies incorporating body composition assessments to better evaluate metabolic vulnerability.

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Publication Details

Journal
Cancers
Published
2025-11-21
DOI
https://doi.org/10.3390/cancers17233727
Primary Topic
Cancer Risks and Factors
Type
article
Field-Weighted Citation Impact
0.00
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article

Inverse Association Between METS-IR and Lung Cancer Risk: The Role of BMI in a Nationwide Korean Cohort

Seok Jae Huh, Minkook Son, Bo-Kyung Shine, In Hwa Jeong et al.
Cancers
Cancer Risks and Factors
article

Inverse Association Between METS-IR and Lung Cancer Risk: The Role of BMI in a Nationwide Korean Cohort

Seok Jae Huh, Minkook Son, Bo-Kyung Shine, In Hwa Jeong, Sang Yi Moon, Hye Ryeon Kim, Jong Yoon Lee, Bong‐Jo Kim
article en

Abstract

In this nationwide cohort study, we observed a significant inverse association between METS-IR and lung cancer risk. However, METS-IR showed limitations in fully explaining lung cancer risk based on insulin resistance alone. These findings highlight the need for future studies incorporating body composition assessments to better evaluate metabolic vulnerability.

CancersVol. 17(23)
Dong-A University Hospital (KR), Dong-A University (KR)
Openalex Percentile: Top 51%
Cancer Risks and Factors
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