Efficacy and Safety of Lenvatinib Versus Sorafenib in Recurrent HCC After Liver Transplant: A Multi‐Center Real‐World Study
This study provides real-world evidence that lenvatinib confers superior overall survival over sorafenib in recurrent HCC post-LT, with manageable toxicity. As LT indications expand, these findings support lenvatinib as a preferred first-line treatment. Further prospective studies are needed to confirm these results and optimize post-LT treatment strategies.
Authors
- Silvia Foti
- Silvia Camera (ORCID: https://orcid.org/0000-0001-8203-1684)
- Tomotake Shirono (ORCID: https://orcid.org/0000-0002-2662-6779)
- Francesca Salani (ORCID: https://orcid.org/0000-0001-7749-8634)
- Margherita Rimini (ORCID: https://orcid.org/0000-0002-4047-2585)
- Federica Lo Prinzi (ORCID: https://orcid.org/0000-0002-0408-5721)
- Naoya Sakamoto (ORCID: https://orcid.org/0000-0003-0061-059X)
- Goki Suda (ORCID: https://orcid.org/0000-0003-0098-9106)
- Naoshi Nishida (ORCID: https://orcid.org/0000-0002-9111-5668)
- Masatoshi Kudo (ORCID: https://orcid.org/0000-0002-4102-3474)
- Mara Persano (ORCID: https://orcid.org/0000-0003-3600-0232)
- Federica Invernizzi (ORCID: https://orcid.org/0000-0001-8072-0152)
- Caterina Vivaldi (ORCID: https://orcid.org/0000-0001-9307-2326)
- Shigeo Shimose (ORCID: https://orcid.org/0000-0003-2068-8386)
- Michele Ferrara (ORCID: https://orcid.org/0000-0002-3142-483X)
- Francesco Vitiello (ORCID: https://orcid.org/0000-0002-3568-0232)
- Sara Lonardi (ORCID: https://orcid.org/0000-0002-7593-8138)
- Mario Domenico Rizzato (ORCID: https://orcid.org/0000-0002-8322-2842)
- Takuya Sho (ORCID: https://orcid.org/0000-0001-7943-3842)
- Laura Passeri (ORCID: https://orcid.org/0000-0001-7885-0636)
- Gianluca Masi (ORCID: https://orcid.org/0000-0001-8329-8989)
- Federico Rossari (ORCID: https://orcid.org/0000-0003-4493-6380)
- Caterina Soldà (ORCID: https://orcid.org/0000-0002-2914-6674)
- Silvia Cesario
- Kazuomi Ueshima (ORCID: https://orcid.org/0000-0002-7577-5789)
- Andrea Casadei‐Gardini (ORCID: https://orcid.org/0000-0001-6289-7202)
- Takashi Niizeki
- Antonio De Rosa
Institutions
- Kurume University (JP)
- University of Pisa (IT)
- University of Padua (IT)
- Vita-Salute San Raffaele University (IT)
- Università Campus Bio-Medico (IT)
- Hokkaido University (JP)
- Istituto Oncologico Veneto (IT)
- IRCCS Ospedale San Raffaele (IT)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
- Azienda Ospedaliera Universitaria Pisana (IT)
- Istituto di Ricovero e Cura a Carattere Scientifico San Raffaele (IT)
- Kindai University (JP)
Publication Details
- Journal
- Hepatology Research
- Published
- 2025-11-21
- DOI
- https://doi.org/10.1111/hepr.70076
- Citations
- 1
- Primary Topic
- Hepatocellular Carcinoma Treatment and Prognosis
- Type
- article
- Field-Weighted Citation Impact
- 1.32