Interaction of nanodrug delivery systems via fibroblasts in colorectal cancer
CAF-targeted nanodrug delivery offers a transformative opportunity to address long-standing barriers in CRC therapy. Future advances will depend on the integration of multi-omics CAF subtyping, rational combination regimens, and clinically scalable nanocarriers to translate these strategies into a lasting clinical benefit.
Authors
- Benno Weigmann (ORCID: https://orcid.org/0000-0002-2398-0844)
- Ying Liu (ORCID: https://orcid.org/0000-0003-0634-8158)
- Mingrui Li (ORCID: https://orcid.org/0009-0008-8654-7002)
- Wenpeng Wang
Institutions
- Friedrich-Alexander-Universität Erlangen-Nürnberg (DE)
- Tianjin Medical University Cancer Institute and Hospital (CN)
- Dazhou Central Hospital (CN)
Publication Details
- Journal
- Expert Opinion on Drug Delivery
- Published
- 2025-11-21
- DOI
- https://doi.org/10.1080/17425247.2025.2593979
- Primary Topic
- Nanoplatforms for cancer theranostics
- Type
- article
- Field-Weighted Citation Impact
- 0.00