Automatability and validity of methods for the quantification of intra-/Intermuscular adipose tissue in conventional MRI: a systematic review

This systematic review highlights gaps in validation and automation of IMAT/IMF quantification methods using conventional MRI sequences. We provide guidance for researchers and clinicians aiming to implement these techniques in routine assessments. Transitioning from qualitative to quantitative MRI assessments requires standardization and automation to improve reproducibility and clinical applicability. Automation plays a key role in integrating these methods into clinical workflows, reducing manual effort, and increasing efficiency. By fostering the development of computer-aided solutions, this review supports the advancement of reliable and accessible IMAT/IMF quantification methods that have the potential to transform musculoskeletal imaging and patient care.