Utilising bioinformatics and molecular docking technology to explore the underlying mechanisms of intervertebral disc degeneration with potential therapeutic drugs and formulas
This study identified CYP1B1 and TNFAIP6 as important targets for IDD, developed a predictive nomogram, and explored the application of TCM herbal formulae, providing new insights into the clinical treatment and prescription development of IDD.
Authors
- Lei Guo (ORCID: https://orcid.org/0000-0003-2055-7618)
- Junchang Liu (ORCID: https://orcid.org/0000-0002-1210-4515)
- Xue Bai (ORCID: https://orcid.org/0000-0003-2309-521X)
- Cheng Wang (ORCID: https://orcid.org/0000-0003-1268-4625)
- Xiaofeng Cui (ORCID: https://orcid.org/0000-0003-2761-3934)
- Tian Yukui
Institutions
- Xinjiang Medical University (CN)
- Inner Mongolia Autonomous Region Hospital of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Journal of Global Health
- Published
- 2025-11-21
- DOI
- https://doi.org/10.7189/jogh.15.04298
- Primary Topic
- Spine and Intervertebral Disc Pathology
- Type
- article
- Field-Weighted Citation Impact
- 0.00